Carrol William* and George Masakay
Young adults are most commonly affected by Multiple Sclerosis (MS), a multifaceted and complex condition that affects their capacity for job and social interaction. For MS patients, bodily and cognitive impairments are the main causes of a poor Quality of Life (QoL). In MS, the prevalence of Cognitive Impairment (CI) varies from 34% to 65%, based on the age at disease onset and the length of the disease. Furthermore, the definition of CI and the amount of neuropsychological batteries used both affect this prevalence in different ways. It has been suggested that a number of factors, including disease phenotype (relapsing or progressive), fatigue, depression, the degree of brain tissue damage, and motor-cognitive reserve, significantly contribute to the decline in total cognitive function. The growing body of research indicates that patient with MS have deficits in less studied cognitive areas like theory of mind, pragmatics, metacognition, prospective memory, etc., which could be impacted in the lack of overall CI. More recent computerised cognitive testing methods have made it possible to use battery designs that are more thorough. Due to the unreliability of studies with bigger sample sizes, their application is still somewhat restricted.