Adnan Burak Bilgiç
Introduction:Multiple sclerosis is a chronic demyelinating central nervous system disease. MS is the most common neurological disease among young adolescents. Diagnosis is achieved with diagnostic criteria.Most cases of MS are sporadic, but about 20 percent of them are familial. Materials and Method:363 familial and 3053 sporadic MS patients, who were followed up in Trabzon Karadeniz Technical University, Faculty of Medicine, Neurology Clinic, MS Outpatient Clinic and Samsun OnDokuzMayıs University, Faculty of Medicine, Neurology Clinic, MS Outpatient Clinic and were registered in the MS database, were retrospectively analyzed. Results: A total of 3416 MS patients were included in the study. 363 of these patients were familial and 3053 were sporadic MS patients. Our familial MS prevalance was 10.6%. Discussions:Our familial MS rate is 10.6%, which is consistent with current MS studies19,20.Looking at the literature, our low prevalence rate compared to some studies might be a result of our high patient count and genetic polymorphism. In familial MS cases, it is thought that the disease starts at an earlier age, the progression is faster, and the rate of conversion to secondary progressive MS is again higher and in a shorter time.