Nagaraju Bantu, Rathnamma vakita
"The acute toxicity tests were conducted during certain intervals in various concentrations of Dimethoate. The physical and chemical analyses of water were carried out by following APHA methods. While treating with Dimethoate, the percentage of fish mortality was assessed during 24, 48, 72 and 96 hours. The estimated lethal concentration values along with 95% confidence limits of Dimethoate were found to be 17.532 mg/l (16.781-19.877), 17.321 mg/l (16.521-18.134), 16.721 mg /l (16.063-17.952), 16.350 mg/l (15.388-17.143), mg/l for 24, 48, 72, and 96 h, respectively. In sub lethal and lethal exposure, the glycogen and protein levels was decreased, minimum percentage of protein depletion was (22.21%) in kidney and maximum percentage was (49.80%), in liver, were observed, the depletion of glycogen content minimum in kidney (18.73%), and maximum in liver (80.14%), the fish was exposed to sub lethal and lethal concentrations for 8 days, The decrease in protein content in various tissues might also be due to inhibition of metabolizing enzymes by administration of agro chemicals. Decline protein levels in early periods due to stress in metabolic process and impairment of protein synthesis machinery in fish."