保拉·安德烈亚·奥尔蒂斯·马林、安德烈斯·费利佩·塞古拉·阿维拉、胡安·卡米洛·阿尔西亚·加尔松、戴安娜·马塞拉·罗德里格斯·安德拉德、何塞·丹尼尔·塞拉·雷耶斯、罗莎娜·玛利亚·巴比伦尼亚·耶佩斯、丹尼尔·福雷罗·赫纳奥、埃德温·亚历杭德罗·巴隆·穆阿奥斯、威廉·毛里西奥·普列托·贝尔特拉n 和胡安·大卫·维加·帕迪拉
Objective: To conduct a review of the literature about sepsis and septic shock in adults.
Methodology: An extensive literature search using multiple databases (Medline, Embase, Scopus, and Science Direct) was used to identify articles from 2013 to 2019 that evaluated the sepsis and septic shock. The keywords “sepsis” and “septic shock” were used. Approximately 1,200 abstracts were identified initially and of these, 35 artic les were selected.
Results: Sepsis is a major cause of death, disability, and cost to the health care system. The new definition of sepsis is “life-threatening organ dysfunction caused by a dysregulated host response to infection” the current management of sepsis primarily involves early resuscitation (Administer intravenous fluid, mean arterial pressure ≥ 65 mmHg, normalize lactate, use vasopressors), and infection control (The current guidelines recommend initiation of intravenous antimicrobials within 1 hour of recognition of sepsis and septi c shock).
Conclusion: Sepsis and septic shock should be diagnosed and treated effectively to reduce morbidity and mortality in intensive care units and emergency departments.