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Therapeutic Agents Targeting Gene Expression Modifications, | 107099

欧洲临床肿瘤学杂志

ISSN - 2732-2654

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Therapeutic Agents Targeting Gene Expression Modifications, Epigenetic Drugs Show Promise in Treating Diseases Like Cancer and Neurological Disorders, Crucial for Precision Medicine Advancements

Allen Robert

Epigenetics investigates heritable, reversible gene regulatory mechanisms beyond DNA sequence, including phosphorylation, acetylation, ubiquitination, and methylation of DNA and histones. Recent research highlights epigenetics' role in illnesses like cancer, and neurological, metabolic, and cardiovascular conditions. Reversible epigenetic changes offer therapeutic potential, with existing use of epigenetic drugs in certain neurological disorders and tumors. This survey discusses major diseases with epigenetic involvement and emerging medications for treatment.